Tri-n-butylphosphine

CAS: 998-40-3
Molecular Formula: C12H27P
Molecular Weight: 202.3165
Product description:And the most commonly used three different ligand phosphorus reagents, tributyl phosphine is a nucleophilic reagent. It is a relatively weak alkali (pKa in MeNO3 = 8.70; in methanol pKa = 5.60), using solvent without strict oxygen, but need to use inert gas protection, if exposed to the air can produce severe oxidation reaction, generate oxygen tributyl phosphine and dibutyl phosphite phosphonic acid butyl ester. Sulfide and sulphur ester synthesis tributyl phosphine and disulfide and alcohol reaction can generate corresponding sulfide and Bu3PO; And disulfide and carboxyl reaction can get sulphur ester (type 1) [1]. Catalytic addition reaction of carbonyl and alkene Because of tributyl phosphine with nucleophilic attack after double bond can lead to migration, electron cloud addition reaction to occur.