Chlormethine hydrochloride

CAS: 55-86-7
Molecular Formula: C5H12Cl3N
Molecular Weight: 192.51
Product description:Used for clinical tumor is one of the drugs, as a representative of the other alkylating agent antitumor drug, its derivatives still occupies a certain position in the clinical treatment. This class of drugs have lively alkylation genes, and cell amino, sulphur, carboxyl and phosphate, affect the cell's metabolism, leading to cell death. Belong to the cell cycle non-specific medicine. After this product enters the body, hydrolytic release of chloride ions in the body, to become a free radical, by intramolecular cyclization, forming highly active ethylene imine ion, can occur with deoxyribonucleic acid alkylation, effecting the metabolism of nucleic acid, inhibiting cell mitosis, has the strong cytotoxic effect.