Fisetin

Description:Fisetin is a flavonol, a structurally distinct chemical substance that belongs to the flavonoid group of polyphenols. It can be found in many plants, where it serves as a colouring agent. Its chemical formula was first described by Austrian chemist Josef Herzig in 1891.Fisetin is a potent sirtuin activating compound (STAC), an agent that modulates sirtuins. It is therefore a caloric restriction mimetic candidate, a drug that has been shown to be able to alleviate ageing effects in certain model organisms such as the yeast S. cerevisiae, the nematode C. elegans[5] and the fruit fly D. melanogaster.Whether such effects can be replicated in humans is currently still not entirely clear and remains an issue of scientific research and debate.