L-Hydroxyproline

CAS:51-35-4
Product Description:L-hydroxyproline, is a common non-proteinogenic amino acid, abbreviated as HYP, e.g., in Protein Data Bank.
L-Hydroxyproline is produced by hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase following protein synthesis (as a post-translational modification). The enzyme catalysed reaction takes place in the lumen of the endoplasmic reticulum. Although it is not directly incorporated into proteins, hydroxyproline comprises roughly 4% of all amino acids found in animal tissue, an amount greater than seven other amino acids that are translationally incorporated.