Chartreusin
Product description:Chartreusin is a potent anti-proliferative agent originally derived from Streptomyces chartreusis. This compound has been shown to be a potent inhibitor of the catalytic activity of topoisomerase II. Experiments have reported that Chartreusin binds to GC-rich tracts in DNA, inhibits RNA synthesis, and causes single-strand scission of DNA via formation of free radicals. Additionally, this agent has been shown to inhibit formation of several DNA-protein complexes.
CAS No.:6377-18-0
Synonyms: Lambdamycin;
Molecular formula: C32H32O14
Molecular weight:640.6
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