Losartan Free Base
CAS: 114798-26-4
Molecular Formula: C22H23ClN6O
Molecular Weight: 422.91
Product description:Light yellow solid, melting point of 183.5 ~ 183.5 ℃. PKa: 5 ~ 6.The first oral peptide angiotensin Ⅱ receptor antagonist. It is mainly used for essential hypertension.Through the direct effect of vascular smooth muscle to lower blood pressure, in blood vessel and nerve effector synaptic by reducing the indirect sympathetic output and lower blood pressure. Step-down valley/peak ratio is 60% ~ 87%.
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