Clavulanic acid
Product description:Clavulanic acid is a beta-lactamase inhibitor (marketed by GlaxoSmithKline, formerly Beecham) combined with penicillin group antibiotics to overcome certain types of antibiotic resistance. It is used to overcome resistance in bacteria that secrete beta-lactamase, which otherwise inactivates most penicillins. In its most common form, the potassium salt potassium clavulanate is combined with amoxicillin (co-amoxiclav, trade names Augmentin, Synulox [veterinary], and others) or ticarcillin.The substance is also under investigation as a NAALADase inhibitor with purported antidepressant and aphrodisiac properties.Clinical trials are underway on XR ("Serdaxin") and IR ("RX-10100", "Zoraxel") formulations by Rexahn in the US.Clavulanic acid is an example of a clavam.
CAS No.:58001-44-8
Synonyms: (2R,3Z,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular formula: C8H9NO5
Molecular weight: 199.16
Structure:
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