Antimycin A

Product description:Antimycins are a group of secondary metabolites produced by Streptomyces bacteria.It is the active ingredient in Fintrol, a chemical piscicide (fish poison) used in fisheries management and in the catfish industry.
Mechanism of action:Antimycin A binds to the Qi site of cytochrome c reductase, thereby inhibiting the oxidation of ubiquinol in the electron transport chain of oxidative phosphorylation. The inhibition of this reaction disrupts the formation of the proton gradient across the inner membrane. The production of ATP is subsequently inhibited, as protons are unable to flow through the ATP synthase complex in the absence of a proton gradient. This inhibition also results in the formation of quantities of the toxic free radical superoxide.
It has also been found to inhibit the cyclic electron flow within photosynthetic systems along the proposed ferredoxin quinone reductase pathway.
CAS No.:1397-94-0
Synonyms: antipiriculin;levoristatin;virosin;antibiot-720A; 
Molecular formula:  C28H40N2O9  
Mol. mass:548.63 g/mol