Warfarin
CAS: 81-81-2
Molecular Formula: C19H16O4
Molecular Weight: 308.33
Product description:This drug for the indirect effect of coumarin oral anticoagulants, by inhibiting the synthesis of vitamin K in the liver cell clotting factor Ⅱ, Ⅶ, Ⅸ, warfarin warfarin Ⅹ, thus play a role of anticoagulation. Liver enzyme systems of carboxyl particles to the clotting factor glutamate into gamma carboxyl glutamic acid, the latter to combine with calcium ions, can play the clotting activity. This drug is used to suppress carboxyl enzyme, and the above factors and without direct confrontation of has been synthesized, must wait for relatively depletion in the body, these factors will play an anticoagulant effect, so this medicine works slowly, only effective in the body, after stopping drug efficacy duration is longer, until the vitamin K dependent factor to gradually return to a certain concentration, anticoagulant effect disappears).
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