Venlafaxine

CAS: 93413-69-5
Molecular Formula: C17H27NO2
Molecular Weight: 277.4
Product description:Mainly through the drug at the same time blocking NE reuptake and 5 - HT, higher concentration of NE and 5 - HT and give play to the role of double antidepressant, heavy intake of dopamine (DA), only a slight inhibition. For M choline receptor, adrenaline alpha 1, alpha, beta 2 receptor, histamine H1 receptor almost no affinity. 0 - to its active metabolites methyl enlafaxine may also inhibit 5 - HT and NE heavy intake, activity is lower than prototype drug. Research has shown that this product in small doses is mainly inhibiting the reuptake of 5 - HT, large doses of 5 - HT and NE reuptake inhibition. The drug for 5 - HT reuptake inhibition weaker than selective 5 - HT heavy uptake inhibitor (SSRI); On NE reuptake inhibition is also weak in some tricyclic antidepressants (TCA) or selective NE reuptake inhibitor.