Sertindole
CAS: 106516-24-9
Molecular Formula: C24H26ClFN4O
Molecular Weight: 440.94
Product description:Benzene indole derivatives, this product is for 5 - HT2A and 5 - HT2C receptor and dopamine D2 receptor and alpha 1 - adrenergic receptor has a strong affinity. But it is low for 5 - HT2 than D2, this product can not cause the A9 nigra striatum dopamine neurons way depolarization inactivation, means that the low resistance to adverse reactions of neurons. But the product of neurons A10 (channel of the middle edge and middle cortex) active, means that have strong antipsychotic effect. Although there are some arguments on the significance of depolarization block, it has a local antipsychotic effect is certain. For the limbic system, are known to be involved in dopamine neurons of nerve stability of antipsychotic.
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