Semustine

CAS: 13909-09-6
Molecular Formula: C10H18N3O2Cl
Molecular Weight: 247.72182
Product description:This product is a yellow crystal powder of pink, light sensitive. Almost insoluble in water, soluble in ethanol, acetone and other organic solvents.This product is a cell cycle non-specific drug, at the G1 / S border, or S early cell the most sensitive, also have inhibition to G2. This product into the body after its molecules from ammonia formamide key break into two parts, one part for chlorine rimantadine, will from the formation of vinyl chloride solution carbenium ion, give play to the role of alkylation, make the DNA chain rupture, RNA and protein by alkylation, this related to the antitumor effect; The other part of ammonia acyl part into isocyanate, or converted to ammonium formate again, in order to play a role of ammonia formylation.