Sebivo
CAS: 3424-98-4
Molecular Formula: C10H14N2O5
Molecular Weight: 242.23
Product description:This product is a natural thymine DNA nucleoside natural L enantiomer, is a synthetic thymine DNA nucleoside class against hepatitis b virus DNA polymerase drugs. In cells under the action of kinase phosphorylation to adenosine, active metabolites with hepatitis b virus in the natural substrate thymine adenosine 5 '- competition, inhibit the activity of the hepatitis b virus DNA polymerase; By integrating to the hepatitis b virus DNA, causing the hepatitis b virus DNA chain extension terminated. And inhibit the hepatitis b virus DNA chain of the first and second chain synthesis. Suitable for treatment with hepatitis b virus activity copy evidence, accompanied by increasing transaminase or liver histological lesions of liver function, activity of compensatory adult chronic hepatitis b.
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