Quinoxaline

CAS: 91-19-0
Molecular Formula: C8H6N2
Molecular Weight: 130.15
Product description:White crystalline. Melting temperature 28 ℃ (29 and 30 ℃), the boiling point 229 ℃, 140 ℃ (5.33 kPa), 108-110 ℃ (1.6 kPa), relative density 1.1334 (40/4 ℃), the refractive index of 1.6231 (40 ℃). Soluble in water, alcohol, ether, benzene. The goods of the melting temperature of 37 ℃ a hydrate.By o-phenylendiamine with glyoxal by cyclization. In response to the pot add water, sodium bisulfite, stirring, slowly add glyoxal, temperatures to rise to 75-80 ℃, white crystal precipitation. Continue stirring for 10 min, and then add water and o-phenylendiamine, in 75-80 ℃ heat 1 h. Cooled to 50 ℃, using sodium carbonate neutralization to pH = 8, heated to 60 ℃, let stand points to the water, after a quick content 80% of benzene and pyrazine, yield of 90%.As the intermediate of pyrazinamide anti-tb drugs.