Picolinic acid

CAS: 98-98-6
Molecular Formula: 6H5NO2
Molecular Weight: 123.11
Product description:White needle crystal. Ice melting point of 134-134 ℃, soluble in acetic acid, hardly soluble in ether, chloroform and carbon disulfide.To add 50 g2 - methyl pyridine to 2500 ml water, heating mixing, add 90 g of potassium permanganate, about 1 h after add a second 90 g of potassium permanganate. Add 500 ml water and continue heating, 2-2.5 h until the purple disappear. Strain the manganese dioxide precipitation, cooling, washing with hot water. Condensed the filtrate decompression, filtering. Concentrate with concentrated hydrochloric acid acidification to Congo red acid after evaporation to dry, with the 250 ml95 % ethanol boiled backflow of 1 h. Filter, filter cake, were extracted with 95% ethanol with ethanol filtrate and extract, ventilation with dry hydrogen chloride, until crystal began to precipitate. Cooling to 10 ℃, recanalization hydrogen chloride to distillation and leaching picolinate hydrochloride, after drying to 43-44 g (hydrochloride melting point of 210-210 ℃).Organic synthesis intermediates.