Palonosetron Hydrochloride

CAS: 135729-62-3
Molecular Formula: C19H25ClN2O
Molecular Weight: 332.87
Product description:An inhibition of nausea and vomiting medicine, belongs to the new type of high selectivity, high affinity 5 - HT3 receptor antagonist, it can block the gag reflex center of presynaptic 5 - HT peripheral neurons. The excitement of receptors, and 5 - HT directly affect the central nervous system. Receptor descendants through the vagus nerve after the excitement of impulse function, blocking the vagus nerve endings in the intestinal, stop signals to 5 - HT. Receptor trigger zone, reduce the incidence of nausea and vomiting. Clinically for the treatment of the medium and heavy to vomit sexual chemotherapy drugs cause acute and delayed nausea and vomiting. Because of its high potency and less side effects, long half-life (about 40 h), and the characteristics of small dosage and attention.