Nebivolol hydrochloride

CAS: 152520-56-4
Molecular Formula: C22H25F2NO4HCL
Molecular Weight: 441.9
Product description:Of the third generation is a potent and selective beta-blockers, the strength of the block 1 receptor beta for beta 2 receptor 290 times, and the peso bisoprolol for 26 times, atenolol is 15 times, general naylor is 1.9 times. So this product has higher selectivity, does not cause bronchial smooth muscle and vascular smooth muscle contraction, not endogenous to the sympathetic activity.Impact on cardiac function and hemodynamics, nai will bisoprolol has no obvious negative inotropic effect, on the contrary, it has certain protective effect to the cardiac function, can reduce cardiac preload, and cardiac afterload unchanged or slightly down. Application of nai will los then can increase ejection fraction in patients with heart failure, and pulmonary artery pressure and pulmonary capillary pressure has no obvious change.