Moxonidine

CAS: 75438-57-2
Molecular Formula: C9H13Cl2N5O
Molecular Weight: 278.14
Product description:New kind of central antihypertensive drug, it is a kind of imidazoline receptors I1 highly selective agonist affinity. According to the different species, the organization and the ligand, the product of imidazoline receptors I1 selectivity than alpha 2 adrenergic receptor selectivity of up to 600 times, in the body and the central imidazoline receptors I1 is the combination of related to the degree of blood pressure to drop significantly. Animal experiment with imidazoline receptor sites have an affinity for a alpha 2 adrenergic receptor antagonists, after pretreatment can offset this product cause blood pressure to drop. This product is a kind of alpha in vitro selective 2 adrenergic receptor agonist, than alpha 1 288 times more adrenaline receptors. This product the antihypertensive effect and has no obvious relation alpha 2 adrenergic receptors.