Methotrexate sodium
CAS: 15475-56-6
Molecular Formula: C20H21N8O5.Na
Molecular Weight: 476.427
Product description:Orange yellow crystalline powder. For folic acid resistant agents, is the activity of folic acid, folic acid and some amino acids such as methionine and serine biosynthesis of one carbon unit vectors. After the drug combined with enzyme, can make the deoxidization thymidylic acid (dTMP) synthesis, DNA synthesis obstacle, still can prevent the synthesis of purine nucleotides, interfere with the protein synthesis, as one of the basic clinical antitumor drug, leukemia and solid tumor effectively. Clinically for acute leukemia, choriocarcinoma, osteosarcoma, breast cancer, testicular cancer treatment is effective.
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