Megestrol

CAS: 3562-63-8
Molecular Formula: C22H30O3
Molecular Weight: 342.47
Product description:Because the progesterone kind drug injected directly into the endometrial cavity caused by the change caused by the effect obviously. Also, the product of the mechanism of action of the anticancer effect of breast cancer is unclear. But through the experiment prove that megestrol on 3 t3 - L1 fibroblasts have promote differentiation, before make fat cells into fat cells. This pair of fat cells to promote differentiation may prompt megestrol mechanism in vivo. Megestrol is an efficient progesterone, in addition to the compatibility for oral contraceptives with estrogen, separately use the product as a short-acting contraceptives. This product is absorbed from the gastrointestinal tract, mainly from the urine, can also from the eduction of excrement and urine, metabolites of glucuronic acid glucoside. Although this product (megestrol acetate) on the exact mechanism of the anti-tumor effect of endometrial cancer is still unknown, but generally considered by progesterone resistance effect of the pituitary gland. There is also evidence suggests local effect on the lining of the uterus.