Ibrutinib
CAS: 936563-96-1
Molecular Formula: C25H24N6O2
Molecular Weight: 440.5
Product description:Bruton tyrosine kinase (BTK) inhibitor, used in the treatment of chronic lymphocytic leukemia (CLL) and cell lymphoma (MCL). MCL and CLL all belong to the B cell non-hodgkin's lymphoma, is difficult to cure and recurrent, commonly used chemical immunotherapy does not have targeted, grade 3 or 4 often occur. According to lu for nicole and B lymphocyte formation, differentiation, necessary for information transmission and BTK, targeted to inhibit the activity of BTK irreversible, effectively inhibit tumor cell proliferation and survival; And oral absorb quickly, after 1 ~ 2 h the largest blood drug concentration, adverse reactions belong to grade 1 or 2, will be a new choice for the treatment of CLL and MCL.
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