Fotemustine

CAS: 92118-27-9
Molecular Formula: C9H19ClN3O5P
Molecular Weight: 315.69
Product description:A glass type of antineoplastic drugs, alkylation and ammonia formylation activity, animal experiments show that also has broad-spectrum antitumor activity. The chemical structural formula contains a alanine biological electronic ligand (amino - 1 - ethyl phosphate), make it easier to penetrate cells and through the blood brain barrier, in the urea nitrate drugs, its penetration is strongest, but the body remove is slower than other drugs. Its mechanism of action and nitrogen mustard are similar, so it is also called fu tai nitrogen mustard, and DNA in the body of enzyme action, inhibition of DNA and RNA synthesis, toxicity and respectively under nitrogen mustard. Clinical management is mainly used in the treatment of primary malignant brain tumors and disseminated malignant melanoma (including brain inside). Second can also be used in the central nervous system tumors, non-small cell lung cancer, malignant lymphoma and kidney cancer, etc.