Epirubicin
CAS: 56420-45-2
Molecular Formula:C27H29NO11
Molecular Weight: 543.5193
Product description:Belong to the antibiotic antitumor medicine. For the isomers of doxorubicin, mechanism of action is directly embedded between nuclear DNA bases on, interfere with the transcription process, prevent the formation of the mRNA, thereby inhibiting the synthesis of DNA and RNA. In addition, the table of adriamycin on topology isomerase Ⅱ has inhibitory effect. For a cell cycle non-specific drug, for a variety of portability tumors are effective. Compared with adriamycin, curative effect is equal or slightly higher, but less toxicity on the heart.Used in acute leukemia and malignant lymphoma, breast cancer, bronchial lung cancer, ovarian cancer, kidney tumor, soft tissue sarcoma, bladder cancer, testicular cancer, prostate cancer, gastric cancer, liver cancer, including primary hepatocellular carcinoma (HCC) and metastatic carcinoma) and medullary thyroid carcinoma and other solid tumors.
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