Enalapril

CAS: 75847-73-3
Molecular Formula: C20H28N2O5
Molecular Weight: 376.4467
Product description:(1) step-down and hydrolysis in the liver of enalaprilat, become a kind of competitive angiotensin converting enzyme inhibitors, angiotensin Ⅰ cannot convert angiotensin Ⅱ, plasma renin activity increased as a result, aldosterone secretion decreased, vascular resistance decreased. Enalaprilat also interfere with the slow degradation of phthalein also reduce vascular resistance. This product is considered mainly by inhibiting renin - angiotensin aldosterone system and lower blood pressure, but also effective for low renin activity of high blood pressure. (2) reducing cardiac load, heart failure when this product expansion of artery and vein, reduce the peripheral vascular resistance or after load, reduce the pulmonary capillary pressure or preload, also reduce pulmonary vascular resistance, improve cardiac output, prolonged exercise tolerance.