Diphenyl chlorophosphate

CAS:2524-64-3
Molecular Formula: C12H10ClO2P
Molecular Weight: 252.6334
Product description:Synthesis of enol phosphate ester ketone or ester and diphenyl phosphoryl chloride hydrochloride.results enol phosphate ester. Enol ester is a very useful intermediates in synthesis, it can alkylate and metal, such as the grignard reagent (1), alkyl aluminum reagent (type 2) , alkyl tin reagent (type 3) [ and other reaction, alkylation olefins by high yield rate. Alpha, beta unsaturated ketones enolization and after treated with LDA (PhO) 2 pocl get 2 enol phosphate ester reaction, and then by the [4 + 2] cyclization to Diels - Alder adduct (4) . Hexene ketone and weaker pro dienes in reaction, requires the use of AlCl3 Lewis acid catalysis. Under the condition of light entrainment, diphenyl phosphate and adjacent groups form free radical ion pair, cause rearrangement (5) and n-cyclohexylmaleimide (6).