Cyproterone
CAS: 2098-66-0
Molecular Formula: C22H27ClO3
Molecular Weight: 374.91
Product description:Abnormal sex hormones and gonadotrophin is used in the treatment of male sexual desire, women hirsutism, acne, precocious puberty and prostate cancer.After oral dosing, cyproterone were completely absorbed within larger doses. Taking cyproterone acetate 50 mg up to maximum serum concentrations of about 140 ng/ml, tmax is about 3 hours. After that, the drug serum concentration in 24-120 - h period of decline, terminal half-life of 43.9 + / - 12.8 h. Cyproterone acetate in the determination of serum total clearance value of 3.5 + / - 1.5 ml/min/kg. Cyproterone acetate metabolism through various channels, including hydroxylation and binding reaction. The main metabolites in human plasma is 15 beta hydroxy derivative.
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