Cortisone

CAS: 53-06-5
Molecular Formula: C21H28O5
Molecular Weight: 360.44
Product description:White crystalline powder. Decomposition Mp220-224 ℃ (part), than the polarimetric [alpha] 25 d + 209 ° (1.2%, 1.2% ethanol), [alpha] 25546 + 269 ° (0.125%, benzene). Soluble in methanol, ethanol, acetone. Slightly soluble in ether, chloroform and benzene; Poorly soluble in water, aqueous solution is neutral. In concentrated sulfuric acid in orange red, and green fluorescence.Mainly applied to the adrenal cortex hypofunction and pituitary function disorder replacement therapy, can be used for allergic and inflammatory diseases. This product can be quickly absorbed by the digestive tract in liver tissue of hydrocortisone conerted to live and play effect, can quickly to work, after oral and absorb slowly intramuscular injection. Its pharmacological effects similar to prednisone, but curative effect is poorer. Cortisol can cause myocardial injury and the change of ECG, also has caused the risk of increasing pressure.