Apatinib
CAS: 811803-05-1
Molecular Formula: C24H23N5O
Molecular weight:397.47232
Appearance:white powder
Purity:99%
Storage:Avoid exposure to sunlight,Keep dry
Product description :Apatinib,is a tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2, also known as KDR). It is an orally bioavailable, small molecule agent which is thought to inhibit angiogenesis in cancer cells; specifically apatinib inhibits VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. This agent also mildly inhibits c-Kit and c-SRC tyrosine kinases.
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