Amtolmetin Guacil

CAS: 87344-06-7
Molecular Formula: C24H24N2O5
Molecular Weight: 420.46
Product description:Applicable to rheumatoid arthritis, rheumatoid arthritis, etc. ; Gung ammonia torme butyl pharmacological effects: this product is a new type of non-steroidal anti-inflammatory drugs (NSAIDs). Main effect of these drugs is inhibited oxidase (COX), which inhibit 1 ring oxidase (COX) - 2 (cox-2) and oxidase. COX - 1 has the effect of protection of gastrointestinal mucosa, and the role of cox-2 has cause inflammation. Ring oxidase (COX) is a kind of combined with membrane glycoprotein, which can be arachidonic acid catalytic oxidation of prostaglandin (PG), and the inhibition of cox-2 prevents can cause inflammation of the synthesis of prostaglandin PGE alpha, etc. The effect of this product is selectively inhibit cox-2, and little impact on the COX - 1. Therefore, does not affect the gastric mucosal blood flow, not to increase the secretion of gastric acid, and can promote the formation of gastric mucosa.