Adriamycin

CAS: 23214-92-8
Molecular Formula: C27H29NO11
Molecular Weight: 543.52
Product description:This product belongs to anthracycline-based antitumor drugs, and soft erythromycin structure similar, difference is only in the side chain 14 carbon atoms have a H for hydroxyl replace, contains both fat-soluble anthracene ring ligands, and water-soluble amine, soft brown sugar and acid phenol hydroxyl and alkaline amino, therefore has a strong anti-cancer pharmacological activities. Adriamycin can silk bacterium culture from the chain (Str. PE - ucetius var. Caesius). Because the molecules in the anthracene quinone ring ligands on - structure of hydroquinone, have the ability to accept electronic and provide a neutron, insert between adjacent base pairs of DNA, to produce active free radicals, and the DNA double helix unwinding, DNA chain rupture, inhibit DNA template activity, interfere with the transcription process, prevent the mRNA synthesis. Also may cause cell membrane rupture, presents the cytotoxic effect, cell cycle non-specific drug.