4-Aminoacetophenone

CAS: 99-03-6
Molecular Formula: C8H9NO
Molecular Weight: 135.16
Product description:By nitrobenzene between ethyl ketone with iron powder reduction and, to add water to the reaction tank, the stir with iron powder and slowly add industrial hydrochloric acid. Again into installments between nitrobenzene ethyl ketone. The heating reflux 6 h. Cooling to 30 ℃, and strong hydrochloric acid in the reaction liquid acid. Filtration, the filtrate with ammonia to weakly alkaline, solid precipitation. Between rejection filter, filter cake for amino acetophenone. Yield of 85%.Pale yellow sheet from ethanol, melting point 98-99 ℃, boiling point of 289-290 ℃, soluble in alcohol, insoluble in water. Part of the volatile in the water vapor.For the synthesis of phenylephrine and hypnotic drugs to drugs, etc., and can be used as raw material in organic synthesis.