Lupulon

Product name : Lupulon 
Synonyms : b-bitter acid; b-lupulic acid
CAS No :  468-28-0
Molecular Formula : C26H38O4
Molecular Weight :  414.58
Product description : 
a bitter crystalline antibiotic that is obtained from lupulin and is effective against fungi and various bacteria.Prisms from 90% methanol, mp 92-94°. Bitter taste esp in alc soln. Turns yellow and amorphous within a few days with development of an odor. Perfectly stable in vacuo even at 60°. Slightly acid reaction. Monobasic acid. Optically inactive. Soluble in methanol, ethanol, petr ether, hexane, isooctane. Slightly sol in neutral or acidic aq solns. Forms a sodium salt which is readily sol in water. The addition of 0.1% ascorbic acid exerts a marked protective action on the bacteriostatic activity of lupulon steamed or autoclaved at a concentration of 4 ppm in phosphate buffers at pH 6.5 and 8.5. LD50 in mice, rats (mg/kg): 525, 100 orally (Hänsel, Wagener).