Mafenide

Product name : Mafenide 
Synonyms : SML;Sulfamylon;Bensulfamide;Mafenide;Homosulfamin;
CAS No . : 138-39-6
Molecular Formula :  C7H10N2O2S  
Mol. mass : 186.233 g/mol 
Product description :
Mafenide (INN; usually as mafenide acetate, trade name Sulfamylon) is a sulfonamide.It is used to treat severe burns.Mafenide (Sulfamylon) can interfere with the kidney's role in hydrogen ion excretion, resulting in metabolic acidosis.Mafenide is a topical sulfonamide used as adjunctive therapy of second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms including Pseudomonas aeruginosa. Mafenide is metabolized to a carbonic anhydrase inhibitor, which could result in metabolic acidosis. This drug was approved by the FDA in 1948. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns.