Polyinosinic acid-polycytidylic acid
Product name : Polyinosinic acid-polycytidylic acid
Synonyms : Polyinosinic:polycytidylic acid copolymer
CAS No. : 24939-03-5
Molecular Formula : C10H13N4O8P.C9H14N3O8P
Molecular Weight : 671.41
Product description :
Polyinosinic:polycytidylic acid (usually abbreviated poly I:C) is an immunostimulant. It is used in the form of its sodium salt to simulate viral infections.Poly I:C is known to interact with toll-like receptor (TLR) 3, which is expressed in the membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system.
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