Ristocetin
Product name : Ristocetin
Synonyms : Spontycine;RistonSpontin;Ristomycin;
CAS No. : 1404-55-3
Molecular Formula : C94H108N8O44
Molecular Weight : 2053.89052
Product description :
Ristocetin is an antibiotic, obtained from Amycolatopsis lurida, previously used to treat staphylococcal infections. It is no longer used clinically because it caused thrombocytopenia and platelet agglutination. It is now used solely to assay those functions in vitro in the diagnosis of conditions such as von Willebrand disease (vWD) and Bernard-Soulier syndrome. Platelet agglutination caused by ristocetin can occur only in the presence of von Willebrand factor multimers, so if ristocetin is added to blood lacking the factor (or its receptor -- see below), it will not coagulate.
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