Phthalide

CAS: 87-41-2
Molecular Formula: C8H6O2
Molecular Weight: 134
Product description:This product is a white solid, m.p. 72 ~ 74 ℃, 290 ℃, b.p. relative density 1.636, soluble in water, soluble in toluene and other organic solvents.By the development of formyl imine reduction. Will begin in sodium hydroxide solution zinc powder and cooling below 5 ℃, to join the copper sulfate solution, the mix slowly phthalates formyl imide, control temperature not to exceed 8 ℃, bi, insulation in 5-8 ℃ 1.5 h. Temperature ammonia 3 h, cooling, filtering, the filtrate with concentrated hydrochloric acid neutralization to pH = 1, heat to boil 1 h, mixing the cooling crystallization, filtration, washed to neutral and dry at low temperature, content of 95% of phthalide, yield of 80%.As the intermediate of fine chemicals. Used in the production of 1, 4 - dichloro anthraquinone dye intermediates, 1 - chloro anthraquinone, anticoagulants phenyl indan diketone, fungicide phthalide, anxiolytics about equality.